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Alzheimer’s Disease and Choroidal Thickness

What is it about?

Although choroidal thickness is considered to be potentially useful for early diagnosis or as a follow-up tool, the role of the choroidal vasculature in the pathogenesis of AD is unclear.To fill this gap in knowledge, this study was to investigate the association between retinal choroidal properties and the pathology of AD by determining choroidal thickness, hippocampus volume, cognitive functions, and plasma BACE1 activity.

Why is it important?

Our findings showed a general tendency of choroid thinning as the cognitive function declined. Although choroidal thickness was not a potential indicator for early stage AD, it was valuable in monitoring AD progression.

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Mo Li
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