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Brain activity reflects the frequency of flickering light flashing at 40 Hz

What is it about?

We examined measurements of brainwave activity recording during routine examination of 1464 patients of varying age. Patients looked at flickering light at 40 Hz. This induces a rhythm in their brainwave activity at the same, i.e. 40 Hz, frequency. We found that there were individual differences in the susceptibility to the response but that advancing age did not appear to fundamentally alter the response.

Why is it important?

Flickering light may be a way to influence the brain's metabolism and immune activity. This has previously been explored in mice models of Alzheimer's disease as a potential treatment. Patients with Alzheimer's Disease are often old and it is not known to what extent age might affect the light stimulation effect. Basic physiology experiments are often carried out on young people, but since most patients with Alzheimer's Disease are old, it is important to know if the response to flickering changes substantially with age or not. We found that is does not. This is relevant baseline knowledge for assumptions underlying future research into the potential therapeutics effects of light stimulation in Alzheimer's Disease.

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Ivan Zibrandtsen
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