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Metal-rich air pollution possibly linked to Alzheimer's disease

What is it about?

We have found iron-rich air pollution nanoparticles in the human brain. Excess iron is toxic to brain cells. Iron-rich air pollution nanoparticles are abundant at roadsides (released from brake wear and exhaust emissions) and can be inhaled htrough the nose and into the brain via the olfactory nerve. It is known that dementia incidence is higher for people who live in proximity to major roads. Exposure to the iron- and associated metal-rich nanoparticles may be a risk factor for developing Alzheimer's and other brain diseases.

Why is it important?

We provide for the first time evidence of a plausible route by which exposure to air pollution particles might be causing Alzheimer's and other brain diseases.

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The following have contributed to this page:
Barbara Maher
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