Understanding cerebral amyloid angiopathy (CAA) and its inflammatory subtypes is crucial. Patients with CAA may experience recurring episodes known as amyloid spells, which can be mistaken for seizures or mini-strokes. For instance, we encountered a 65-year-old woman initially diagnosed with seizures, but further evaluation revealed she was experiencing amyloid spells. MRI scans showed evidence of small brain bleeds and cortical hemorrhages typical of CAA, along with brain swelling indicating CAA-related inflammation. This highlights the importance of accurate diagnosis, as some of these patients have underlying risk factors for stroke and require careful assessment of benefits of primary or secondary stroke prevention strategies, with some benefiting from treatment with immunosuppressants. It's also important to understand that patients with CAA-related inflammation (CAARI) are different from those with vasculitis. In vasculitis, patients typically show a quick decline in mental status. However, with amyloid spells, which occur in CAARI, the symptoms come back again and again over time and develop more slowly