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Results and effects of the treatment of patients with carcinoma of unknown primary site (CUP)

What is it about?

Carcinoma of unknown primary site (CUP) refers to 1–5% of all head and neck neoplasms. Very often, the primary site remains difficult to determine. Squamous cell carcinoma is the most frequent histopathological type diagnosed in the head and neck region. The study presents diagnostic difficulties and the methods of diagnosing and the therapy of CUP and primary sites.

Why is it important?

CUP patients have often negative results of biopsy and imaging tests. Some procedures give a possibility of detecting the primary site and improves the results of treatment and survival of CUP patients. Combined therapy, including surgical treatment and chemoradiotherapy, gives the best therapeutic results in CUP patients.

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The following have contributed to this page:
Tomasz Zatonski
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