What is it about?
• Evidence on 11 psychosocial interventions compared with treatment as usual (TAU) was reviewed, based on 9 systematic reviews of 192 trials and 30 additional trials (N=23,921 patients). • Various functional outcomes were improved with assertive community treatment, cognitive behavioral therapy (CBT), family interventions, psychoeducation, social skills training, supported employment, and early interventions for first-episode psychosis (FEP). Quality of life was improved with CBT and early interventions for FEP. Relapse was reduced with family interventions, psychoeducation, illness self-management, and early interventions for FEP. Although not typically a target outcome, core illness symptoms were improved with CBT, family interventions, and illness self-management.