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A case report on short-term memory loss after recreational opioid use

What is it about?

In a patient who presented with acute onset amnesia after a reported fentanyl overdose, brain imaging showed abnormal signal in the memory circuits and on follow-up imaging at 4 months, there was an approximate 10% reduction in hippocampal volume and persistent neuropsychological deficits in episodic memory.

Why is it important?

Serial MRIs of the brain in a patient with an acute, opioid-related amnestic syndrome reveals both transient and residual changes in the hippocampi, providing quantifiable structural data to support the persistent cognitive impairments observed in this case.

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The following have contributed to this page:
Monroe Butler
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