Consequences of Recurrent Depression: Is Stopping Effective Antidepressant Medications Ever Safe
What is it about?
Depression is a chronic illness, such as diabetes, cardiovascular illnesses and schizophrenia. Even with successful treatments 50% to 85% of individuals will experience at least another episode of depression in their lifetime. The decision to stop successful antidepressant treatments can be life changing and life saving. Current approaches would need to be transformed from attainment of clinical remission to attainment and maintenance of lifetime wellness. Similar to targeted long-term treatment outcomes for cancers and cardiovascular illnesses, "5-year survival” would equate "5-year wellness". For some, maintaining wellness may require indefinite continuation of treatment.
Why is it important?
According to the World Health Organization, depression is the world’s leading cause of disability. If patients do not reach and sustain clinical and functional remission, episodes tend to recur with greater severity and with lessening responsivity to conventional treatments.