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Transition from substance-induced psychosis to schizophrenia or bipolar disorder

What is it about?

A register based study of more than 3000 substance-induced psychosis cases found a six-year cumulative transition rate to schizophrenia spectrum disorder of 28%, and to bipolar disorder of 5%. The risk of transition to schizophrenia spectrum disorder was higher in men who were young, had repeated emergency admissions, and where the psychosis was induced by cannabis.

Why is it important?

Our findings show that substance-induced psychosis is as a major risk factor for schizophrenia. This should inform and guide the health service.

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Eline Rognli
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