(function(doc, html, url) { var widget = doc.createElement("div"); widget.innerHTML = html; var script = doc.currentScript; // e = a.currentScript; if (!script) { var scripts = doc.scripts; for (var i = 0; i < scripts.length; ++i) { script = scripts[i]; if (script.src && script.src.indexOf(url) != -1) break; } } script.parentElement.replaceChild(widget, script); }(document, '

What is it about?

The shared risk factors and clinical features in schizophrenia and bipolar disorder may be linked via mitochondrial dysfunction. This study investigated whether mitochondrial-related gene expression and higher-order gene co-expression relationships differ in both disorders in cortex and specific neuronal populations. Schizophrenia and bipolar disorder do not appear to share similar mitochondrial-related alterations. The selective and coordinated down-regulation of energy production genes in schizophrenia is consistent with the effects of chronic reductions in pyramidal neuron firing. Enhancement of this activity may serve as a therapeutic target.

Read more on Kudos…
The following have contributed to this page:
Jill GLAUSIER
' ,"url"));