Objective: Suicide by firearm is the most common suicide method of young men in Switzerland. Between March 2003 and end of February 2004, the number of Swiss soldiers was halved due to an army reform (Army XXI), leading to decreased availability of guns nationwide. We investigated the pattern of general suicide rate and the suicide rate by shooting before and after the Army XXI invention. Method: Using a naturalistic study design, we compared suicide rates before (1995 to 2003) and after the intervention (2004 to 2008) among the affected population (men aged 18 to 43) and compared these to two control groups. Data was retrieved from the Swiss Federal Statistical Office. Interrupted Time Series methodology was applied to control for temporal trends already in existence, such as unemployment rates. Alternative methods (Poisson regression, autocorrelation analysis and surrogate data tests) were used to check validity.