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Pax7+ satellite cells and VO2max

What is it about?

We hypothesized that an active lifestyle reflected in higher VO2max may be associated with greater SC number. As training alters basal p38-mitogen-activated protein kinase (MAPK) activity, which is associated with SC proliferation, SC count may also correlate with this stress signaling kinase.

Why is it important?

SC number is proportional to VO2max, and hence it can be postulated that higher levels of physical activity activate SC proliferation but not fusion, underlining the relevance of exercise in stimulating SC pool size even without injury.

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The following have contributed to this page:
Mari van de Vyver
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