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Crystal structure of Bmh1 (yeast 14-3-3) with human peptide

What is it about?

Yeast proteins and human proteins are far apart in evolution. Here we use X-ray crystallography to show that 14-3-3 proteins are remarkably conserved between man and yeast.

Why is it important?

Our paper shows that 14-3-3 proteins evolved millions years ago and their structure&function remained virtually the same underlying their importance in physiology.

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Evzen Boura
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