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A novel carbapenem-hydrolyzing class C extended-spectrum β-lactamase

What is it about?

In this study, we report the molecular, biochemical, and structural characterization of ADC-68, which is a class C extended-spectrum β-lactamase (cESBL) and carbapenemase, from A. baumannii D015.

Why is it important?

ADC-68 is the first reported enzyme among chromosomal class C β-lactamases to possess class C extended-spectrum β-lactamase and carbapenemase activities.

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Sang Hee Lee
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