Nicknames individuate and identify their bearers and stand out with more socio-cognitive forces than the conventional names within the socio-cultural setting and beyond. In this paper, I examine the sociolinguistic and ethnographic significance of nicknaming among female adolescents in Nigeria with particular emphasis on those living in the Calabar metropolis, Cross River State, South-eastern Nigeria. I take into account the dynamics of female nicknames, their social consequences in group integration and solidarity, sources, and the perception of these nicknames. The study is rooted in Leslie and Skipper (1991) socio-onomastic theory of nicknames which establishes the constitutive, preferential and ad hoc rules of nicknaming in understanding the social construction of the nicknaming process. I, therefore, conclude with the claim that female nicknames are creative, cultural symbols and styles by which female adolescents express themselves as a critical resistance to the stereotypical imaging of women in a conservative society, given their psychological, sexual and aesthetic appeals.